Research Interests

  • Cellular bioengineering
  • Cytoskeletal mechanics
  • Molecular motors
  • Intracellular cargo transport
  • Image processing
  • Microfluidic cell sorting and capture
  • Biosensing
  • Computational fluid mechanics
  • Machine learning

Courses Taught




BIOE 0844

The Bionic Human


BIOE 0944

Honors Bionic Human


BIOE 4441

Capstone Elective: Biomechanics


BIOE 4500

Special Topics: Modelling of Cellular Systems


BIOE 5441



BIOE 5500

Special Topics: Modelling of Cellular Systems


Selected Publications

  • Arpag, G., Norris, S.R., Mousavi, S.I., Soppina, V., Verhey, K.J., Hancock, W.O., & Tüzel, E. (2019). Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors. Biophysical Journal, 116(6), pp. 1115-1126. doi: 10.1016/j.bpj.2019.01.036

  • Kingsley, J.L., Bibeau, J.P., Mousavi, S.I., Unsal, C., Chen, Z., Huang, X., Vidali, L., & Tüzel, E. (2018). Characterization of Cell Boundary and Confocal Effects Improves Quantitative FRAP Analysis. Biophysical Journal, 114(5), pp. 1153-1164. doi: 10.1016/j.bpj.2018.01.013

  • Chinnasamy, T., Kingsley, J.L., Inci, F., Turek, P.J., Rosen, M.P., Behr, B., Tüzel, E., & Demirci, U. (2018). Guidance and Self-Sorting of Active Swimmers: 3D Periodic Arrays Increase Persistence Length of Human Sperm Selecting for the Fittest. Advanced Science, 5(2). doi: 10.1002/advs.201700531

  • Bibeau, J.P., Kingsley, J.L., Furt, F., Tüzel, E., & Vidali, L. (2018). F-actin mediated focusing of vesicles at the cell tip is essential for polarized growth. Plant Physiology, 176(1), pp. 352-363. doi: 10.1104/pp.17.00753

  • Bangasser, B.L., Shamsan, G.A., Chan, C.E., Opoku, K.N., Tüzel, E., Schlichtmann, B.W., Kasim, J.A., Fuller, B.J., McCullough, B.R., Rosenfeld, S.S., & Odde, D.J. (2017). Shifting the optimal stiffness for cell migration. Nature Communications, 8. doi: 10.1038/ncomms15313

  • Greenberg, M.J., Arpag, G., Tüzel, E., & Ostap, E.M. (2016). A Perspective on the Role of Myosins as Mechanosensors. Biophysical Journal, 110(12), pp. 2568-2576. doi: 10.1016/j.bpj.2016.05.021

  • Pyrpassopoulos, S., Arpag, G., Feeser, E.A., Shuman, H., Tüzel, E., & Ostap, E.M. (2016). Force generation by membrane-associated myosin-I. Scientific Reports, 6. doi: 10.1038/srep25524

  • Arpag, G., Shastry, S., Hancock, W.O., & Tuezel, E. (2014). Transport by Populations of Fast and Slow Kinesins Uncovers Novel Family-Dependent Motor Characteristics Important for In Vivo Function (vol 107, pg 1896, 2014). BIOPHYSICAL JOURNAL, 107(12), pp. 3034-3034. doi: 10.1016/j.bpj.2014.11.014

  • Asghar, W., Velasco, V., Kingsley, J.L., Shoukat, M.S., Shafiee, H., Anchan, R.M., Mutter, G.L., Tüzel, E., & Demirci, U. (2014). Selection of Functional Human Sperm with Higher DNA Integrity and Fewer Reactive Oxygen Species. Advanced Healthcare Materials, 3(10), pp. 1671-1679. doi: 10.1002/adhm.201400058

  • Tasoglu, S., Safaee, H., Zhang, X., Kingsley, J.L., Catalano, P.N., Gurkan, U.A., Nureddin, A., Kayaalp, E., Anchan, R.M., Maas, R.L., Tüzel, E., & Demirci, U. (2013). Exhaustion of racing sperm in nature-mimicking microfluidic channels during sorting. Small, 9(20), pp. 3374-3384. doi: 10.1002/smll.201300020