Biography

Michel A Lemay, PhD is a Professor in the Department of Bioengineering at Temple University. His research group focuses on understanding the functioning and contribution of the spinal circuitry to the control of locomotion, and how this circuitry can be re-engaged for rehabilitation purposes following injury. Dr.Lemay's group uses a number of tools to activate and probe the spinal circuitry, techniques ranging from cellular delivery of neurotrophic factors to electrical stimulation of the spinal cord or its afferent feedback to locomotor re-training and multiunit recording of interneuronal activity during locomotion. Prior to coming to Temple University, Dr. Lemay was a Professor in the Department of Neurobiology and Anatomy at Drexel University College of Medicine, and a Principal Investigator in the Spinal Cord Research Center at this institution. Dr. Lemay received his PhD and MS in Biomedical Engineering from Case Western Reserve University, and trained as a post-doctoral fellow under Drs. Neville Hogan and Emilio Bizzi at the Massachusetts Institute of Technology.

Research Interests

  • Neural Engineering
  • Spinal Cord Role in Movement
  • Spinal Cord Injury & Plasticity
  • Spinal Circuitry
  • Biomechanics
  • Neuroprosthesis

Courses Taught

Number

Name

Level

BIOE 3301

Biomedical Signals and Systems

Undergraduate

BIOE 3402

Design Elective: Biodesign

Undergraduate

Selected Publications

  • McMahon, C., Kowalski, D.P., Krupka, A.J., & Lemay, M.A. (2023). Lumbar multiunit activity power spectrum during air stepping in the spinal cat: evidence for a flexor-dominated rostrocaudally distributed locomotor center. J Neurophysiol, 129(5), pp. 1072-1085. United States. doi: 10.1152/jn.00310.2022

  • Park, H., Klishko, A.N., Oh, K., Zhang, C., Grenga, G., Herrin, K.R., Dalton, J.F., Kistenberg, R.S., Lemay, M.A., Pitkin, M., DeWeerth, S.P., & Prilutsky, B.I. (2023). Electrical Stimulation of Distal Tibial Nerve During Stance Phase of Walking May Reverse Effects of Unilateral Paw Pad Anesthesia in the Cat. Motor Control, 27(1), pp. 71-95. United States. doi: 10.1123/mc.2022-0096

  • McMahon, C., Kowalski, D.P., Krupka, A.J., & Lemay, M.A. (2022). Single-cell and ensemble activity of lumbar intermediate and ventral horn interneurons in the spinal air-stepping cat. J Neurophysiol, 127(1), pp. 99-115. United States. doi: 10.1152/jn.00202.2021

  • Vahedipour, A., Short, M.R., Timnak, A., Maghsoudi, O.H., Hallowell, T., Gerstenhaber, J., Cappellari, O., Lemay, M., & Spence, A.J. (2021). A versatile system for neuromuscular stimulation and recording in the mouse model using a lightweight magnetically coupled headmount. J Neurosci Methods, 362, p. 109319. Netherlands. doi: 10.1016/j.jneumeth.2021.109319

  • Moukarzel, G., Lemay, M.A., & Spence, A.J. (2021). A MATLAB application for automated H-Reflex measurements and analyses. Biomed Signal Process Control, 66. England. doi: 10.1016/j.bspc.2021.102448

  • Marchionne, F., Krupka, A.J., Smith, G.M., & Lemay, M.A. (2020). Intrathecal Delivery of BDNF Into the Lumbar Cistern Re-Engages Locomotor Stepping After Spinal Cord Injury. IEEE Trans Neural Syst Rehabil Eng, 28(11), pp. 2459-2467. United States. doi: 10.1109/TNSRE.2020.3027393

  • Higgin, D., Krupka, A., Maghsoudi, O.H., Klishko, A.N., Nichols, T.R., Lyle, M.A., Prilutsky, B.I., & Lemay, M.A. (2020). Adaptation to slope in locomotor-trained spinal cats with intact and self-reinnervated lateral gastrocnemius and soleus muscles. J Neurophysiol, 123(1), pp. 70-89. United States. doi: 10.1152/jn.00018.2019

  • Eisdorfer, J.T., Smit, R.D., Keefe, K.M., Lemay, M.A., Smith, G.M., & Spence, A.J. (2020). Epidural Electrical Stimulation: A Review of Plasticity Mechanisms That Are Hypothesized to Underlie Enhanced Recovery From Spinal Cord Injury With Stimulation. Front Mol Neurosci, 13, p. 163. Switzerland. doi: 10.3389/fnmol.2020.00163

  • Tiwari, E., Barbe, M.F., Lemay, M.A., Salvadeo, D.M., Wood, M.W., Mazzei, M., Musser, L.V., Delalic, Z.J., Braverman, A.S., & Ruggieri, M.R. (2019). Acute bladder decentralization in hound dogs: Preliminary results of effects on hypogastric nerve electroneurograms and detrusor pressure responses to spinal root and hypogastric nerve stimulation. PLoS One, 14(4), p. e0215036. United States. doi: 10.1371/journal.pone.0215036