Dr. Patil earned a Ph.D. in Biomedical Engineering from Vanderbilt University in Nashville, TN, where he also served as a post doctoral research fellow in the Center for Biomedical Optics. Prior to joining Temple University, Dr. Patil was a Research Assistant Professor in the Department of Biomedical Engineering at Vanderbilt University. His research is focused on the development of label-free, biochemically specific, optical imaging and spectroscopy techniques for screening and diagnosis of disease, intra-operative surgical guidance, and applications to priority issues in global health. Dr. Patil’s work has been included in journals such as Optics Letters, Journal of Biomedical Optics, and Optics Express.

Research Interests

  • Optical Imaging & Spectroscopy
  • Disease Screening & Diagnosis
  • Intra-Operative Surgical Guidance
  • Optical Technologies in Global Health

Courses Taught




BIOE 3301

Biomedical Signals and Systems


BIOE 4333

Applied Biospectroscopy


BIOE 4451

Capstone Elective: Biomedical Imaging


BIOE 5333

Applied Biospectroscopy


BIOE 5451

Biomedical Imaging


Selected Publications

  • Haifler, M., Pence, I., Sun, Y., Kutikov, A., Uzzo, R.G., Mahadevan-Jansen, A., & Patil, C.A. (2018). Discrimination of malignant and normal kidney tissue with short wave infrared dispersive Raman spectroscopy. Journal of Biophotonics, 11(6). doi: 10.1002/jbio.201700188

  • Dumont, A.P. & Patil, C. (2018). Development of accelerated Raman and fluorescent Monte Carlo method. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 10490. doi: 10.1117/12.2293831

  • Dumont, A.P., Harrison, B., Mccormick, Z.T., Kumar, N.G., & Patil, C.A. (2017). Development of mobile phone based transcutaneous billirubinometry. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 10055. doi: 10.1117/12.2257428

  • Pence, I.J., Patil, C.A., Lieber, C.A., & Mahadevan-Jansen, A. (2015). Discrimination of liver malignancies with 1064 nm dispersive Raman spectroscopy. Biomedical Optics Express, 6(8), pp. 2724-2737. doi: 10.1364/BOE.6.002724

  • Tucker-Schwartz, J.M., Lapierre-Landry, M., Patil, C.A., & Skala, M.C. (2015). Photothermal optical lock-in optical coherence tomography for in vivo imaging. Biomedical Optics Express, 6(6), pp. 2268-2282. doi: 10.1364/BOE.6.002268

  • Patil, C.A., Pence, I.J., Lieber, C.A., & Mahadevan-Jansen, A. (2014). 1064 nm dispersive Raman spectroscopy of tissues with strong near-infrared autofluorescence. Optics Letters, 39(2), pp. 303-306. doi: 10.1364/OL.39.000303

  • Poole, K.M., McCormack, D.R., Patil, C.A., Duvall, C.L., & Skala, M.C. (2014). Quantifying the vascular response to ischemia with speckle variance optical coherence tomography. Biomedical Optics Express, 5(12), pp. 4118-4130. doi: 10.1364/BOE.5.004118

  • Mahadevan-Jansen, A., Patil, C.A., & Pence, I.J. (2014). Raman spectroscopy: From benchtop to bedside. In Biomedical Photonics Handbook, Second Edition: Biomedical Diagnostics (pp. 759-802). doi: 10.1201/b17289