Tang, Yuan

Research Assistant Professor, Mechanical Engineering

Bio

Yuan Tang is a Research Assistant Professor in the Department of Mechanical Engineering at Temple University. He earned his doctorate in Biomedical Engineering from Florida International University. He served as a post-doctoral fellow at Widener University prior to joining Temple University. His current research interests are the development of targeted drug delivery systems utilizing natural or induced inflammatory responses in human endothelium, including the synthesis and characterization of nano-sized drug carriers, drug payload internalization and controlled release. The work conducted by Dr. Yuan Tang is motivated but not restricted by applications in the fields of nanotechnology, molecular imaging, drug delivery and radiation oncology. Dr. Yuan Tang has several publications in high-impact peer-reviewed journals such as Nanomedicine and Pharmaceutical Research.

Degrees

  • Ph.D, Biomedical Engineering, Florida International University, Miami, FL, 2010
  • B.S, Shanghai Second Medical University, Shanghai, China, 2002

Academic Appointments

  • Research Assistant Professor, Temple University, 2014 - present
  • Postdoctoral fellow, Widener University, 2011 - 2014

Recent Publications

  • Tang Y, Wang Y, Kiani MF, Wang B. Classification, Treatment Strategy, and Associated Drug Resistance in Breast Cancer. Clin Breast Cancer. 2016 May 13. pii: S1526-8209(16)30108-2. doi: 10.1016/j.clbc.2016.05.012. [Epub ahead of print].
  • Soroush F, Zhang T, King DJ, Tang Y, Deosarkar S, Prabhakarpandian B, Kilpatrick LE, Kiani MF. A novel microfluidic assay reveals a key role for protein kinase C δ in regulating human neutrophil-endothelium interaction. J Leukoc Biol. 2016 May 17. pii: jlb.3MA0216-087R. [Epub ahead of print].
  • Tang Y, Wang Y, Deosarkar S, Soroush F, Kiani MF, Wang B. Fast, Stable Induction of P-Glycoprotein-mediated Drug Resistance in BT-474 Breast Cancer Cells by Stable Transfection of ABCB1 Gene, Anticancer Research. 2015;35(5):2531-8.
  • Tang Y, Gan X, Cheheltani R, Curran E, Lamberti G, Krynska B, Kiani MF, Wang B. Targeted Delivery of Vascular Endothelial Growth Factor Improves Stem Cell Therapy in a Rat Myocardial Infarction Model, Nanomedicine: Nanotechnology, Biology and Medicine. 2014;10(8):1711-8.
  • Lamberti G, Tang Y, Prabhakarpandian B, Wang Y, Pant K, Kiani MF, et al. Adhesive interaction of functionalized particles and endothelium in idealized microvascular networks. Microvascular research. 2013;89:107-14.

Research Interest

  • Novel nano-carrier design and fabrication for targeted drug delivery and molecular imaging
  • Development of biomimetic microfluidic platforms for drug delivery
  • Novel combinational strategies for cancer treatment