Peter I. Lelkes

Chair and Professor in Bioengineering

Office Hours

Room 811
Monday: 3:00 PM - 4:30PM
Tuesday: 4:00 PM - 5:30 PM


Peter I. Lelkes, PhD, is the Laura H. Carnell Professor and Founding Chair of the Department of Bioengineering in the College of Engineering at Temple University. Dr. Lelkes is also the Inaugural Director of the Institute for Regenerative Medicine and Engineering (TIME) at Temple University’s School of Medicine. Prior to that he was from 2000-2011 the Calhoun Chair Professor in the School of Biomedical Engineering, Science and Health Systems at Drexel University in Philadelphia. 

Dr. Lelkes has received numerous honors and awards, nationally and internationally. Amongst them a Forchheimer Visiting Fellowship at the Hebrew University, Jerusalem, Honorary Professorships at the University of Applied Sciences Aachen, Germany and the Changchun Institute of Polymer Chemistry and Physics, Chinese Academy of Sciences, and a Distinguished Visiting Fellowship of the Royal Academy of Engineering at Imperial College, London, UK. In 2011 he was inducted as a Fellow of the AIMBE (American Institute for Medical and Biological Engineering) and received the 2012 Ben Franklin Key Award from IEEE, the Institute of Electrical and Electronics Engineers.  

Throughout his career of 30+ years, Dr. Lelkes has received over $18 million in funding from numerous federal and private funding sources. Dr. Lelkes has organized several Keystone conferences, published more than 175 peer-reviewed papers, authored more than 50 books / book chapters and made more than 400 presentations nationally and internationally. 

In his “free-time” Dr. Lelkes is an active chamber musician and likes to hike in the mountains.


  • Ph.D. (Dr. rer nat), RWTH Aachen, Germany, 1977
  • M.Sc. (Dipl. Phys.), RWTH Aachen, Germany, 1974

Academic Appointments 

  • Laura H. Carnell Professor and Chair, Bioengineering Department, Temple University, January 2012-present
  • Calhoun Chair Professor, School of Biomedical Engineering, Science and Health Systems, Drexel University, January 2010-December 2011
  • Full Professor, University of Wisconsin Medical School, September 1991-August 2010

Recent Publications 

  • Mondrinos, M.J., Jones, P.L,, Finck, C.M., and Lelkes, P.I. (2014) Engineering De Novo Assembly of Fetal Pulmonary Organoids. Tissue Eng Part A. 2014 Jun 25. [Epub ahead of print]
  • Har-el, Y., Gerstenhaber, J.A., Brodsky, R., Huneke, R.B., and Lelkes, P.I. (2014) Electrospun Soy Protein Scaffolds as Wound Dressings: Enhanced Reepithelialization in a Porcine Model of Wound Healing. Wound Medicine, 5:9–15.
  • Şenel-Ayaz, H.G., Perets, A., Ayaz H., Gilroy, K.D., Govindaraj, M., Brookstein, D., and Lelkes, P.I (2014) Textile-Templated Electrospun Anisotropic Scaffolds for Regenerative Cardiac Tissue Engineering Biomaterials. 35:8540-8552.
  • Cohen, G., Ettinger, K., Lecht, S., Lelkes, P.I., and Lazarovici, P. (2014) Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells. J Mol Neurosci. 2014 Jul 31. [Epub ahead of print]
  • Pimton, P, Lecht, S., Schulman, E.S., and Lelkes, P.I. (2014) Hypoxia enhances differentiation of mouse embryonic stem cells into definitive endoderm and distal lung cells. Stem Cells Dev. 2014 Sep 16. [Epub ahead of print]
  • Frohbergh, M.E., Katsman, A., Mondrinos, M.J., Stabler, C.T., Hankenson, K.D., Oristaglio, J.,T., and Lelkes, P.I. (2015) Osteointegrative Properties of Electrospun Hydroxyapatite-Containing Nanofibrous Chitosan Scaffolds. Tissue Eng Part A. 21:970-81. PMID: 25336062
  • Lecht, S., Ciaverelli, R.A., Gerstenhaber J.,  Calvete, J.J., Lazarovici, P., Casewell, N.R., Harrison, R., Lelkes, P.I., and Marcinkiewicz, C. (2015) Anti-angiogenic acivities of snake venom CRISP isolated from Echis carinatus sochureki. Biochim Biophys Acta. 1850:1169-1179. PMID: 25665484
  • Malik, R., Lelkes, P.I., and Cukierman E. (2015) Biomechanical and Biochemical Remodeling of Stromal Extracellular Matrix in Cancer. Trends in Biotechnology, 33:230-236. PMID: 25708906
  • Ventresca, E.M., Lecht S., Jakubowski P., Chiaverelli R.A., Weaver M, Del Valle L., Ettinger K., Gincberg G., Priel A., Braiman A., Lazarovici P., Lelkes P.I., and Marcinkiewicz C.  (2015) Association of p75NTR and a9b1 integrin modulates NGF-dependent cellular responses. Cell Signal. 27:1225-1236. PMID: 25748048
  • Weiss, D.J., Chambers, D., Giangreco, A., Keating, A., Kotton, D., Lelkes, P.I., Wagner, D.E., and Prockop, D.J.,  (2015) An Official American Thoracic Society Workshop Report: Stem Cells and Cell Therapies in Lung Biology and Diseases, ATS Subcommittee on Stem Cells and Cell Therapies. Annals of the American Thoracic Society, 12: S79-97. PMID: 25897748
  • Stabler, C.T., Lecht, S., Lazarovici, P., and Lelkes, P.I. (2015) Mesenchymal stem cells for therapeutic applications in pulmonary medicine. Br Med Bull. 115:45-56. PMID: 26063231
  • Stabler, C.T., Lecht, S., Mondrinos, M.J., Goulart, E., Lazarovici, P., and Lelkes PI. (2015) Revascularization of Decellularized Lung Scaffolds: Principles and Progress. Am J Physiol Lung Cell Mol Physiol.309: L1273-L1285. PMID: 26408553
  • Stabler, C.T, Junior, L., Mondrinos, M.E., Marcinkiewicz, C., Lazarovici, P., Wolfson, M.R., and Lelkes, P.I. (2016) Enhanced re-endothelialization of decellularized rat lungs, Tissue Engineering, Tissue Eng Part C Methods. 22:439-50. PMID: 26935764
  • Palukuru, U.P., Hanifi, A., McGoverin, C.M.  Devlin, S., Lelkes, P.I., and Pleshko, N. (2016) Near infrared spectroscopic imaging assessment of cartilage composition: Validation with mid infrared imaging spectroscopy. Analytica Chimica Acta, 926:79-87. PMID: 27216396
  • Kischkel S, Bergt S, Brock B, von Grönheim J, Herbst A, Epping MJ, Matheis G, Novosel E, Schneider J, Warnke P, Podbielski A, Roesner JP, Lelkes PI, Vollmar B. (2017) In-vivo testing of extracorporeal membrane ventilators: iLA-activve® vs. prototype I-lung®. ASAIO J., Jan 4. Epub ahead of print], PMID: 28092273

Research Interest 

Currently Prof. Lelkes directs a broad interdisciplinary program in regenerative tissue engineering, focusing on nanotechnology-based biomaterials and soft tissue engineering, employing developmental biological principles to enhance the tissue-specific differentiation of embryonic and adult stem cells towards pulmonary, cardiac and neuronal lineages.

Funding Sources

Dr. Lelkes’ basic and translational research has been support by federal (NIH, NSF, NASA, DOE) and state funding agencies (NTI and Dept. of Commerce, Tobacco Settlement Funds) and private Foundations, including the Coulter Foundation. Dr. Lelkes has been the team leader for tissue engineering at the Nanotechnology Institute of Southeastern Pennsylvania (NTI) and was the Co-Director of PATRIC, the Pennsylvania Advanced Textile Research and Innovation Center, focusing on BioNanoTextiles and Stem Cell Biology.