Mohammad F. Kiani

Professor in Mechanical Engineering

Office Hours

Monday-Friday
Walk-ins or by appointment

Bio

Dr. Mohammad F. Kiani is Professor of the Department of Mechanical Engineering. Dr. Kiani’s expertise is in biofluid mechanics, targeted drug delivery, and radiation oncology. Dr. Kiani co-founded Engineering World Health with Dr. Robert Malkin, served as its president for several years, and currently serves on its board of directors. Dr. Kiani has also founded several for-profit companies and currently serves as the Chief Scientific Officer for MedVas Concepts, LLC.

Degrees

  • B.S. In Electrical Engineering, University of Oklahoma, 1983
  • M.S. in Biomedical Engineering, Louisiana Tech University, 1987
  • Ph.D. in Biomedical Engineering, Louisiana Tech University, 1990
  • NIH Postdoctoral Fellow, University of Rochester, 1990-1993

Academic Appointments 

  • Professor, Department of Mechanical Engineering, Temple University, Philadelphia, PA, 2014-present
  • Professor and Chair, Department of Mechanical Engineering, Temple University, Philadelphia, PA, 2004-2014
  • Acting Chair, Department of Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, 2003-2004
  • Professor, Department of Biomedical Engineering and Department of Radiation Oncology, University of Tennessee Health Science Center, Memphis, TN, 2002-2004

Recent Publications 

  • Lamberti, G; Prabhakarpandian, B; Garson, C; Smith, A; Pant, K; Wang, B & Kiani, MF (2014) Bioinspired microfluidic assay for in vitro modeling of leukocyte-endothelium interactions. Anal. Chem., 86:8344-8351.

  • Deosarkar, SP; Prabhakarpandian, B; Wang, B; Sheffield, JB; Krynska, B & Kiani, MF (2015) A novel dynamic neonatal blood brain barrier on a chip. PLoS ONE, 10(11):e0142725. doi:10.1371/journal.pone.0142725.
  • Soroush, F; Zhang, T; King, DJ; Tang, Y; Deosarkar, S; Prabhakarpandian, B; Kilpatrick, LE & Kiani, MF (2016) A Novel microfluidic assay reveals a key role for protein kinase C-delta in regulating human neutrophil-endothelium interaction. J. Leukoc. Biol., 100:1027-1035 [Invited Manuscript] [Featured on the Cover].
  • Tang, Y; Soroush, F; Tong, Z; Kiani, MF & Wang, B (2017) Targeted multidrug delivery system to overcome chemoresistance in breast cancer. Int. J. Nanomed., 12:671–681.
  • Tang, Y; Soroush, F; Sheffield, JB; Wang, B; Prabhakarpandian, B & Kiani, MF (2017) A biomimetic microfluidic tumor microenvironment platform mimicking the EPR effect for rapid screening of drug delivery systems. Sci. Rep., In press.

 

 

Research Interest 

The current focus of Dr. Kiani's research is the development of novel techniques for targeting antivascular drugs to irradiated tumors and pro-angiogenic compounds to infracted cardiac tissue. He is also developing a “blood-brain barrier on a chip” to study congenital neurological diseases in children. He currently collaborates with a number of investigators in the US and internationally.

Funding Sources

Dr. Kiani's research has been funded by an Established Investigator Award from the American Heart Association and other research grants from NIH/NHLBI/NCI, NSF, Shriners Hospitals for Children, the Susan G. Komen Foundation, DOD Breast Cancer Research Program, and the Pennsylvania Department of Health.