Tuesday: 12:00 PM - 1:30 PM
Thursday: 12:00 PM - 1:30 PM
Bojana Gligorijevic, PhD, graduated Chemistry at University of Belgrade with an honors thesis in analytical chemistry, isolating active compounds from endemic plants. At Georgetown University, Dr. Gligorijevic’s PhD chemistry thesis took a turn when she first saw a fluorescent microscope. She ended up developing new technologies for automated 4D imaging and analysis of malaria division and metabolic processes. During her postdoctoral training in cancer biology at Albert Einstein College of Medicine, she developed new tools for intravital imaging in mouse models and contributed to the current view of tumor cell intravasation mechanism in tumor microenvironment context.
- B.S. Chemistry, Belgrade University, Serbia, 2001
- Ph.D Chemistry, Georgetown University, Washington, DC 2007
- Assistant Professor, Temple University, 2015 – present
- Instructor, Systems & Computational Biology Department, Albert Einstein College of Medicine, New York, NY, 2012 - 2015
- Research Fellow, Anatomy and Structural Biology Department, Albert Einstein College of Medicine, New York, NY, 2007 - 2012
- A. Bergman, B. Gligorijevic: "Niche Construction Game Cancer Cells Play", in Physics of Cancer collection, European Physics Journal Plus (2015) 130:203 PMCID: PMC5027994
- K. Ismaeili, A. Bergman, B. Gligorijevic "Extracellular matrix cross-linking regulates invadopodia dynamics." BioRxiv 198580 [Preprint]. October 04, 2017 Available from : https://doi.org/10.1101/198580
- F. Tonisen, L. Perrin, K. vand der Dries, A. Cambi, B. Gligorijevic, "EP4 receptor role in invasion of breast carcinoma" European Journal of Cell Biology (2017) PMCID: PMC5362301
- B. Baraymagnai, L. Perrin, K. Esmaeili, B. Gligorijevic: Methods in molecular biology "Intravital imaging of cell migration", Editor Alexis Gautreau, in press
- Gligorijevic B, Bergman A, Condeelis J. (2014) Multiparametric classification links tumor microenvironments with tumor cell phenotype, PLoS Biology 12:e1001995.
- Génot E, Gligorijevic B (2014), Invadosomes in their natural habitat. European Journal of Cell Biology 93:367-79.
- Bergman A, Condeelis JS, Gligorijevic B. (2014), Invadopodia in context, Cell Adhesion and Migration 8:273-9.
- Gligorijevic B, Wyckoff J, Yamaguchi H, Wang Y, Roussos ET, Condeelis J. (2012) N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors, Journal of Cell Science 125:724-34.
- Entenberg D, Wyckoff J, Gligorijevic B, Roussos ET, Verkhusha VV, Pollard JW, Condeelis J. (2011) Setup and use of a two-laser multiphoton microscope for multichannel intravital fluorescence imaging. Nature Protocols 6:1500-20
- Additional publications at Google Scholar and PubMed.
The Gligorijevic lab studies how tumor microenvironments control decision-making of tumor cells. We are currently focused on the investigation of motile tumor cells in the primary tumor with the goal of building a predictive model of tumor cell entry into blood vessels (intravasation). Towards our goal, our primary tool is intravital multiphoton microscopy in animal models, which is combined with classical molecular and cell biology, mathematical and computational modeling, cancer engineering and systems view into a “systems microscopy” approach. Results of our work will be useful in improvement of early diagnosis of metastasis and testing of novel therapeutic agents.
- NCI/NIH K99/R00, Systems microscopy of tumor cell motility in microenvironment context, 2013 - 2018
- Charles H Revson Postdoctoral Fellowship in Biomedical Sciences Program, 2010 - 2012
- Concept Award, Breast Cancer Research Program of Department of Defense 2008 - 2009