Evangelia Bellas

Assistant Professor of Bioengineering

Office Hours

Room 913
Wednesday: 10:30 AM - 12:00 PM
Friday: 10:30 AM - 12:00 PM
Or by Appointment

Bio

Dr. Evangelia Bellas is an Assistant Professor in the Department of Bioengineering at Temple University. Prior to joining Temple University, Dr. Bellas was a postdoctoral fellow in Biomedical Engineering at Boston University and Bioengineering at University of Pennsylvania under the mentorship of Dr. Christopher Chen where she developed 3D in vitro adipose tissue disease models. She received her Ph.D. in Biomedical Engineering at Tufts University mentored by Dr. David Kaplan. Her Ph.D. research focused on developing long-term volume stable silk biomaterials for soft tissue regeneration. This work resulted in 2 patent applications and a start-up. Before starting her Ph.D., Dr. Bellas was at Massachusetts Institute of Technology under the supervision of Drs. Robert Langer and Daniel Kohane, where she worked on biomaterial, drug delivery solutions for prevention of peritoneal adhesions and controlled release formulations for long-term pain management. Her current research focuses on the development of fat-on-chip and (dys)functional adipose tissue models to study how vascularization and interactions with the microenvironment impact tissue health and function.

Degrees

Ph.D. in Biomedical Engineering, Tufts University, 2012

B.S. in Bioengineering, Syracuse University, 2004

Academic Appointments

Assistant Professor, Bioengineering, Temple University, 2016- Present

Visiting Postdoctoral Research Fellow, Wyss Institute for Biologically Inspired Engineering, Harvard University, 2014-2016

Postdoctoral Fellow, Biomedical Engineering, Boston University, 2013-2016

Postdoctoral Fellow, Bioengineering, University of Pennsylvania, 2012-2013

Research Assistant, Massachusetts Institute of Technology, 2004-2007         

 

Selected Publications

Link to full list: http://goo.gl/ajFkoN

·         Bellas E, Alimperti S, Chen CS. Hypoxia Induces a Fibrotic Transition via Tissue Stiffening in a 3D Model of Adipose Tissue. Submitted.

·         Bellas E, Lo T, Fournier E, Brown JE, Abbott RD, Rubin JP, Marra KG, Leisk GG, Kaplan DL. Injectable silk foams for soft tissue regeneration.  Advanced Healthcare Materials 2015;4:452–459.

·         Bellas E, Rollins A, Moreau JE, Lo T, Quinn KP, Fourligas N, Georgakoudi I, Mazan M, Thane KE, Hoffman AM, Kaplan DL, Kirker-Head CA. Equine model for Soft Tissue Regeneration with Silk Biomaterials. Journal of Biomedical Materials Research Part B 2015:103B:1217–1227.

·         Bellas E, Chen CS. Form, Forces and Stem Cell Fate. Current Opinion in Cell Biology. 2014;31:92-97.

·         Bellas E, Marra KG, Kaplan DL. Sustainable 3D tissue model of human adipose tissue.  Tissue Eng Part C Methods. 2013;19(10):745-54.

·         Ward A, Quinn KP, Bellas E, Georgakoudi I, Kaplan DL. Noninvasive metabolic imaging of engineered 3D human adipose tissue in a perfusion bioreactor. PLoS ONE. 2013;8(2):e55696.

·         Bellas E, Panilaitis BP, Glettig DL, Kirker-Head CA, Yoo JJ, Marra KG, Rubin JP, Kaplan DL. Sustained Volume Retention In Vivo with Adipocyte and Lipoaspirate Seeded Silk Porous Scaffolds. Biomaterials. 2013 Apr;34(12):2960-8.

·         Gil ES, Panilaitis B, Bellas E, Kaplan DL. Biofunctionalized Silk Biomaterials for Wound Healing. Adv Healthc Mater. 2013 Jan;2(1):206-17.

·         Bellas E, Seiberg M, Garlick JA, Kaplan DL. In vitro development of a 3D full thickness skin equivalent model using silk and collagen biomaterials. Macromol Biosci. 2012 Dec;12(12):1627-36.

·         Quinn KP, Bellas E, Fourligas NP, Kaplan DL, Georgakoudi I. Quantification of Engineered Adipose Tissue Development Using Multi-Photon Microscopy. Biomaterials. 2012 Jul;33(21):5341-8.

·         Choi J, Bellas E, Gimble J, Vunjak-Novakovic G, Kaplan DL. Lipolytic Function of Adipocyte/Endothelial Co-Cultures. Tissue Engineering Part A. 2011 May;17(9-10):1437-44.

 

Research Interests

  • Adipose Tissue
  • Angiogenesis
  • Microenvironment
  • Cell Mechanics
  • Obesity
  • Disease Models
  • Soft Tissue Regeneration
  • Biomaterials
  • Tissue Engineering
  • Regenerative Medicine